SCHEMBL27471998

SCHEMBL27471998

NC(=O)Nc1ccc(P(=O)(O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.57
ALDH1A1 P00352 3/20 0.55
NPC1 O15118 1/20 0.55
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
GFER P55789 1/20 0.52
KIF11 P52732 6/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
KMT2A Q03164 1/20 0.50
CA2 P00918 2/20 0.48
CA4 P22748 1/20 0.48
CA5A P35218 1/20 0.48
GLA P06280 1/20 0.46
HSD17B10 Q99714 1/20 0.43
CA1 P00915 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3905759 0.98 PEPD (0.55) PEPDALDH1A1NPC1GAAMAPT
SCHEMBL5062623 0.82 PEPD (0.80) PEPDALDH1A1NPC1GAAMAPT
SCHEMBL3899943 0.82 ALDH1A1 (0.52) ALDH1A1GAAMAPTKIF11KMT2A
SCHEMBL3905764 0.80 NPC1 (0.57) PEPDALDH1A1NPC1GAAMAPT
SCHEMBL3897654 0.80 ALDH1A1 (0.50) ALDH1A1GAAMAPTKIF11KMT2A
SCHEMBL8887300 0.79 SMN1; SMN2 (0.59) ALDH1A1NPC1MAPTMEN1KMT2A
SCHEMBL7920846 0.76 POLB (0.76) NPC1MAPTMEN1LMNAKMT2A
SCHEMBL17362396 0.76 CA2 (0.54) ALDH1A1NPC1GAAMAPTMEN1
SCHEMBL7922273 0.75 SIRT1 (0.59) NPC1GAAMEN1LMNAKMT2A
SCHEMBL8922195 0.75 PTPN1 (0.62) NPC1MAPTMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791361-A Positive lithographic printing plate precursor, method for producing same, and method for producing lithographic printing plate 富士胶片株式会社 2019-05-21 CN disclosed
CN-101352451-A Anionic or cationic dendrimer antimicrobial or antiparasitic compositions STARPHARMA PTY LTD (AU) 2009-01-28 CN disclosed
CN-1161128-C Angiogenic inhibitory compounds О 2004-08-11 CN disclosed
CN-1323215-A Inhibition of toxic materials or substances using dendrimers STARPHARMA LTD (AU) 2001-11-21 CN disclosed
CN-1323214-A Antimicrobial or antiparasitic compositions of anionic or cationic dendrimers STARPHARMA LTD (AU) 2001-11-21 CN disclosed