Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201826 | 0.87 | ALDH1A1 (0.34) | POLBALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL4928726 | 0.71 | ALDH1A1 (0.35) | POLBALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL19674785 | 0.71 | CD44 (0.35) | POLBALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL11154303 | 0.71 | TDP1 (0.39) | POLBALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL31096856 | 0.71 | ALDH1A1 (0.35) | POLBALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL2561658 | 0.71 | ALDH1A1 (0.35) | POLBALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL10373232 | 0.70 | CD44 (0.46) | POLBALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL24455092 | 0.70 | CD44 (0.41) | POLBALDH1A1SMN1; SMN2CYP1A2CD44 | |
| SCHEMBL17298234 | 0.70 | CD44 (0.41) | POLBALDH1A1MAPK1SMN1; SMN2CD44 | |
| SCHEMBL20265158 | 0.70 | CD44 (0.46) | POLBALDH1A1SMN1; SMN2CD44CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113316571-A | Pyridine sulfonamide compounds for treating interleukin-1 beta-related disorders | 阿林齐生物制药公司 | 2021-08-27 | — | — | CN | disclosed |