SCHEMBL28617062

SCHEMBL28617062

COc1cc(C=CC(=O)NC2(C(=O)O)CCCCC2)ccc1OCc1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HPGD P15428 3/20 0.52
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
NFKB1 P19838 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
KDM4E B2RXH2 1/20 0.50
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
S1PR1 P21453 2/20 0.49
CA2 P00918 1/20 0.49
CA5A P35218 1/20 0.49
CA9 Q16790 1/20 0.49
S1PR4 O95977 1/20 0.49
MAPK1 P28482 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
GPR35 Q9HC97 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28617061 1.00 ALDH1A1 (0.52) ALDH1A1HPGDHTTSMN1; SMN2RAB9A
SCHEMBL28634987 0.99 ALDH1A1 (0.53) ALDH1A1HPGDHTTSMN1; SMN2RAB9A
SCHEMBL28634985 0.99 ALDH1A1 (0.53) ALDH1A1HPGDHTTSMN1; SMN2RAB9A
SCHEMBL28620446 0.91 ALDH1A1 (0.48) ALDH1A1HPGDHTTSMN1; SMN2RAB9A
SCHEMBL29766253 0.91 ALDH1A1 (0.48) ALDH1A1HPGDHTTSMN1; SMN2RAB9A
SCHEMBL28620444 0.91 ALDH1A1 (0.48) ALDH1A1HPGDHTTSMN1; SMN2RAB9A
SCHEMBL28617056 0.90 ALDH1A1 (0.53) ALDH1A1HPGDHTTKDM4ECA2
SCHEMBL28617059 0.90 ALDH1A1 (0.53) ALDH1A1HPGDHTTKDM4ECA2
SCHEMBL29766340 0.90 ALDH1A1 (0.53) ALDH1A1HPGDHTTKDM4ECA2
SCHEMBL28617049 0.89 ALDH1A1 (0.54) ALDH1A1HPGDHTTSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113233993-B Ferulic acid amide derivative and synthetic method thereof 贵州大学 2022-07-01 CN disclosed
CN-113233993-A Ferulic acid amide derivative and synthetic method thereof 贵州大学 2021-08-10 CN disclosed