Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336746 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL19923214 | 0.87 | CD274 (0.54) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL16554885 | 0.83 | MRGPRX4 (0.50) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL16554820 | 0.82 | CD274 (0.66) | CD274PDCD1 | |
| SCHEMBL19897793 | 0.81 | CD274 (0.47) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30395624 | 0.81 | CD274 (0.47) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL19929643 | 0.80 | PIK3CD (0.49) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL18729371 | 0.80 | CD274 (0.46) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL20540140 | 0.80 | CD274 (0.50) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL29925812 | 0.80 | CD274 (0.46) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307779-B | Heterocyclic substituted biphenyl compound, preparation method and application | 中国药科大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-113307779-A | Heterocyclic substituted biphenyl compound, preparation method and application | 中国药科大学 | 2021-08-27 | — | — | CN | disclosed |