Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17073088 | 0.81 | MAPK1 (0.49) | MAPK1PKMHSD17B10TSHRALDH1A1 | |
| SCHEMBL18541492 | 0.79 | ALDH1A1 (0.66) | MAPK1TSHRALDH1A1ESR1TDP1 | |
| SCHEMBL26901115 | 0.78 | ALDH1A1 (0.51) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7256727 | 0.76 | ESR1 (0.68) | MAPK1TSHRALDH1A1ESR1TDP1 | |
| SCHEMBL5122 | 0.75 | CA1 (0.63) | TSHRALDH1A1ESR1TDP1LMNA | |
| SCHEMBL19214441 | 0.75 | CA1 (0.61) | PKMALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL1953298 | 0.75 | MAPK1 (0.73) | MAPK1PKMHSD17B10TSHRALDH1A1 | |
| SCHEMBL8297889 | 0.74 | CYP2D6 (0.54) | TSHRALDH1A1ESR1TDP1CHRM1 | |
| SCHEMBL23926201 | 0.74 | TSHR (0.53) | MAPK1PKMHSD17B10TSHRALDH1A1 | |
| SCHEMBL23926219 | 0.73 | MAPK1 (0.57) | MAPK1PKMHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113133969-B | Glucose-responsive insulin multivesicular liposome and preparation method and application thereof | 中国药科大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113133969-A | Glucose-responsive insulin multivesicular liposome and preparation method and application thereof | 中国药科大学 | 2021-07-20 | — | — | CN | disclosed |