Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617522 | 0.81 | MAPK1 (0.47) | MAPK1PKMHSD17B10TSHRESR1 | |
| SCHEMBL10488203 | 0.78 | ALDH1A1 (0.70) | MAPK1TSHRESR1ALDH1A1TDP1 | |
| SCHEMBL1953298 | 0.77 | MAPK1 (0.73) | MAPK1PKMHSD17B10TSHRESR1 | |
| SCHEMBL3943866 | 0.76 | ALDH1A1 (0.55) | MAPK1PKMHSD17B10TSHRALDH1A1 | |
| SCHEMBL18200292 | 0.76 | TSHR (0.55) | MAPK1TSHRESR1ALDH1A1TDP1 | |
| SCHEMBL24268514 | 0.76 | MAPK1 (0.36) | MAPK1PKMHSD17B10TSHRESR1 | |
| SCHEMBL23926219 | 0.75 | MAPK1 (0.57) | MAPK1PKMHSD17B10TSHRESR1 | |
| SCHEMBL5028692 | 0.75 | ESR1 (0.72) | MAPK1TSHRESR1ALDH1A1TDP1 | |
| SCHEMBL21104795 | 0.74 | TDP1 (0.66) | MAPK1PKMTSHRESR1ALDH1A1 | |
| SCHEMBL21104588 | 0.74 | TDP1 (0.66) | MAPK1PKMTSHRESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015134467-A1 | METHODS AND COMPOSITIONS FOR DIRECT RADIOACTIVE LABELING OF BIO-ACTIVE MOLECULES AND BUILDING BLOCKS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-09-11 | — | — | WO | disclosed |