Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24538298 | 0.78 | GABRA1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL1457304 | 0.69 | ALDH1A1 (0.39) | GABRA1GABRB2 | |
| SCHEMBL20744683 | 0.67 | GABRA1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL24553957 | 0.66 | — | — | |
| SCHEMBL24553946 | 0.66 | CCR1 (0.43) | GABRA1GABRB2 | |
| SCHEMBL24538284 | 0.66 | GABRA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL1964508 | 0.66 | GABRA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL4663299 | 0.65 | ALDH1A1 (0.42) | — | |
| SCHEMBL29759333 | 0.65 | ALDH1A1 (0.42) | — | |
| SCHEMBL24538287 | 0.64 | GABRA1 (0.33) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824701-B | Pyridinothiazole compound and preparation method and application thereof | 武汉工程大学 | 2021-08-13 | — | — | CN | disclosed |