Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL5178755 | 0.92 | ALDH1A1 (0.47) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| Phthalic Acid SCHEMBL28204947 | 0.90 | KDM4E (0.48) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| Phthalic Acid SCHEMBL28828777 | 0.87 | ALDH1A1 (0.48) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| Adipic Acid SCHEMBL28148639 | 0.86 | FFAR4 (0.49) | MEN1KMT2AALDH1A1TSHRFFAR4 | |
| Phthalic Acid SCHEMBL28338752 | 0.85 | ALDH1A1 (0.52) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| Phthalic Acid SCHEMBL28186885 | 0.84 | MEN1 (0.43) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| Adipic Acid SCHEMBL28472695 | 0.83 | FFAR4 (0.46) | MEN1KMT2AALDH1A1TSHRFFAR4 | |
| Phthalic Acid SCHEMBL28621581 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| Phthalic Acid SCHEMBL1308819 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AKDM4ERECQLALDH1A1 | |
| Phthalic Acid SCHEMBL11211807 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AKDM4ERECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110054883-B | Long-acting washable low-temperature-resistant colorless transparent liquid antistatic agent for rubber and plastic and preparation method thereof | 杭实科技发展(杭州)有限公司 | 2021-09-03 | — | — | CN | disclosed |