Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL28338752 | 0.94 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AKDM4ERECQL | |
| Phthalic Acid SCHEMBL28617575 | 0.92 | MEN1 (0.41) | ALDH1A1FFAR4FFAR1MEN1KMT2A | |
| Phthalic Acid SCHEMBL28621581 | 0.91 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4ERECQL | |
| Hexanoate SCHEMBL27322791 | 0.87 | FFAR4 (0.59) | ALDH1A1FFAR4FFAR1MEN1KMT2A | |
| Adipic Acid SCHEMBL736750 | 0.87 | FFAR4 (0.59) | ALDH1A1FFAR4FFAR1MEN1KMT2A | |
| Phthalic Acid SCHEMBL28828777 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AKDM4ERECQL | |
| Phthalic Acid SCHEMBL1309164 | 0.84 | ALDH1A1 (0.61) | ALDH1A1FFAR1MEN1KMT2AKDM4E | |
| Phthalic Acid SCHEMBL28204947 | 0.82 | KDM4E (0.48) | ALDH1A1FFAR4FFAR1MEN1KMT2A | |
| SCHEMBL5178745 | 0.82 | ALDH1A1 (0.54) | ALDH1A1FFAR4FFAR1MEN1KMT2A | |
| Phthalic Acid SCHEMBL28585942 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957116-B1 | Energy-curable ethylenically unsaturated compositions | MINNESOTA MINING & MFG (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-0726921-B1 | ENERGY-CURABLE CYANATE/ETHYLENICALLY UNSATURATED COMPOSITIONS | MINNESOTA MINING & MFG (US) | 2000-01-12 | — | — | EP | disclosed |
| EP-0957116-A2 | Energy-curable ethylenically unsaturated compositions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-11-17 | — | — | EP | disclosed |
| US-5856022-A | VIBRATION DAMPING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0726921-A1 | ENERGY-CURABLE CYANATE/ETHYLENICALLY UNSATURATED COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1994029369-A1 | ENERGY-CURABLE CYANATE/ETHYLENICALLY UNSATURATED COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-22 | — | — | WO | disclosed |