SCHEMBL28617852

SCHEMBL28617852

CCCCN(CCCC)C[Si](C)(C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
KCNH2 Q12809 4/20 0.41
HTT P42858 1/20 0.41
OPRM1 P35372 2/20 0.40
DRD3 P35462 2/20 0.40
DRD2 P14416 1/20 0.40
OPRD1 P41143 1/20 0.40
OPRK1 P41145 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CHRM2 P08172 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
CHRM1 P11229 1/20 0.39
DRD1 P21728 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468622 0.83 MEN1 (0.41) MEN1KMT2ANPSR1KCNH2HTT
SCHEMBL31468511 0.78 KCNH2 (0.36) MEN1KMT2ANPSR1KCNH2HTT
SCHEMBL31468648 0.77 TP53 (0.37) MEN1KMT2ANPSR1KCNH2HTT
SCHEMBL5801979 0.74 NR1H2 (0.53) MAPT
SCHEMBL8755782 0.73 TSHR (0.39) MEN1KMT2ANPSR1HTTMAPT
SCHEMBL31468521 0.73 HTT (0.35) MEN1KMT2ANPSR1KCNH2HTT
SCHEMBL10393864 0.71 MAPT (0.41) KMT2ATDP1MAPTSIGMAR1
SCHEMBL20482223 0.71 NR1H2 (0.46) MEN1KMT2AKCNH2HTT
SCHEMBL7536048 0.71 NR1H2 (0.46) MEN1KMT2AKCNH2HTT
SCHEMBL28960091 0.71 NR1H2 (0.46) MEN1KMT2AKCNH2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113244761-B Mixed silicone oil for capturing acid gas through phase change and preparation method thereof 昆明理工大学 2023-07-07 CN disclosed
CN-113244761-A Mixed silicone oil for capturing acid gas through phase change and preparation method thereof 昆明理工大学 2021-08-13 CN disclosed