Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669488 | 0.86 | LMNA (0.61) | LMNAKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL27820373 | 0.83 | LMNA (0.57) | LMNAKMT2ARAB9AMEN1NPC1 | |
| Pyrazine SCHEMBL28948452 | 0.82 | LMNA (0.56) | LMNARAB9ANPC1MAPTKDM4E | |
| SCHEMBL14900763 | 0.81 | LMNA (0.59) | LMNAKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL28185044 | 0.81 | LMNA (0.51) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL12085758 | 0.81 | KDM4E (0.55) | LMNAKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL31154476 | 0.81 | KDM4E (0.55) | LMNAKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL29120745 | 0.80 | LMNA (0.50) | LMNAKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL14278920 | 0.80 | LMNA (0.50) | LMNARAB9ANPC1MAPTKDM4E | |
| SCHEMBL12708790 | 0.79 | LMNA (0.57) | LMNAKMT2ARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535422-B | Diamine compound, polyimide film, and flexible display device | 阜阳欣奕华材料科技有限公司 | 2021-08-24 | — | — | CN | disclosed |