Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23064432 | 0.79 | TSHR (0.44) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL28919867 | 0.79 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL17912759 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TSHRHPGDATMHCAR2 | |
| Methacrylic Acid SCHEMBL28912409 | 0.74 | TSHR (0.43) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL959989 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDATM | |
| SCHEMBL7185104 | 0.71 | FNTA (0.41) | ALDH1A1TSHRATMHCAR2ALOX15 | |
| SCHEMBL141466 | 0.71 | EP300 (0.38) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL3847692 | 0.71 | FNTA (0.41) | ALDH1A1TSHRATMHCAR2ALOX15 | |
| SCHEMBL2507515 | 0.69 | TSHR (0.44) | ALDH1A1TSHRHPGDATM | |
| SCHEMBL141468 | 0.69 | TSHR (0.33) | ALDH1A1TSHRHPGDATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226379-A | Nanoparticle encapsulation targeting G protein-coupled receptors in endosomes | 武田药品工业株式会社 | 2021-08-06 | — | — | CN | disclosed |