Tenivastatin

Tenivastatin

SCHEMBL28618339

CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC(O)CC(O)CC(=O)O)[C@H]21.N

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLCO1B1 Q9Y6L6 4/20 0.98
HMGCR P04035 11/20 0.83
HDAC1 Q13547 3/20 0.81
HDAC2 Q92769 3/20 0.81
HDAC6 Q9UBN7 3/20 0.81
SLC22A8 Q8TCC7 1/20 0.63
SLCO1B3 Q9NPD5 1/20 0.63
CYP3A4 P08684 3/20 0.60
USP2 O75604 2/20 0.60
ALDH1A1 P00352 2/20 0.60
TSHR P16473 2/20 0.60
ALOX15 P16050 2/20 0.60
KDM4E B2RXH2 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
NR1I2 O75469 1/20 0.60
ABCB11 O95342 1/20 0.60
NR3C1 P04150 1/20 0.60
PGR P06401 1/20 0.60
ABCB1 P08183 1/20 0.60
ADORA3 P0DMS8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tenivastatin SCHEMBL2987588 1.00 SLCO1B1 (0.98) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL28594405 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL3694911 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL8239454 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL13934502 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL25366987 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL110804 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL14420544 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL28594403 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6
Tenivastatin SCHEMBL14137685 0.99 SLCO1B1 (1.00) SLCO1B1HMGCRHDAC1HDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105853993-B Analogs of 3,5-dihydroxypentanoic acid for osteogenesis 高雄医学大学 2021-08-13 CN disclosed