Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605926 | 0.90 | MEN1 (0.46) | CTSSCTSKCYP17A1EGFRCA2 | |
| SCHEMBL28603103 | 0.84 | IDO1 (0.41) | CTSSCTSKCYP17A1MEN1KMT2A | |
| SCHEMBL28605021 | 0.83 | MEN1 (0.48) | CTSSCTSKCYP17A1EGFRMEN1 | |
| SCHEMBL28602379 | 0.81 | GPR119 (0.44) | CYP17A1MEN1KMT2AIDO1GPR119 | |
| SCHEMBL24454248 | 0.81 | IDO1 (0.40) | CYP17A1EGFRMEN1KMT2AIDO1 | |
| SCHEMBL28609015 | 0.79 | HDAC8 (0.53) | CTSSCTSK | |
| SCHEMBL22125838 | 0.78 | IDO1 (0.41) | CTSSCTSKCYP17A1MEN1KMT2A | |
| SCHEMBL28604647 | 0.78 | GPR119 (0.46) | MEN1KMT2AIDO1GPR119JAK2 | |
| SCHEMBL28607177 | 0.78 | GPR119 (0.46) | CYP17A1MEN1KMT2AIDO1GPR119 | |
| SCHEMBL28604646 | 0.78 | GPR119 (0.46) | MEN1KMT2AIDO1GPR119JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164448-A | Amino acid anilines as small molecule modulators of IL-17 | 利奥制药有限公司 | 2021-07-23 | — | — | CN | disclosed |