Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463259 | 0.83 | NPC1 (0.46) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL20455857 | 0.82 | CYP1A2 (0.56) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL17292958 | 0.81 | MALT1 (0.47) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28619643 | 0.76 | KDM4E (0.42) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL18863029 | 0.71 | KDM4E (0.45) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL17293001 | 0.71 | MALT1 (0.41) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL17293002 | 0.71 | MALT1 (0.41) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL20768126 | 0.71 | ALDH1A1 (0.35) | KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL17293093 | 0.69 | CYP1A2 (0.51) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL17293094 | 0.69 | CYP1A2 (0.51) | KDM4ENPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |