Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28151987 | 1.00 | USP30 (0.52) | USP30LMNANPSR1UCHL1NPC1 | |
| SCHEMBL28629836 | 0.83 | SCN4A (0.50) | LMNANPSR1UCHL1MEN1KMT2A | |
| SCHEMBL28619807 | 0.83 | SCN4A (0.50) | LMNANPSR1UCHL1MEN1KMT2A | |
| SCHEMBL26364475 | 0.80 | USP30 (0.48) | USP30LMNANPSR1UCHL1NPC1 | |
| SCHEMBL30964960 | 0.79 | LMNA (0.48) | USP30LMNANPSR1UCHL1NPC1 | |
| SCHEMBL5427853 | 0.79 | HSD17B10 (0.52) | USP30LMNANPSR1UCHL1NPC1 | |
| SCHEMBL5427850 | 0.79 | HSD17B10 (0.52) | USP30LMNANPSR1UCHL1NPC1 | |
| SCHEMBL2492664 | 0.79 | HSD17B10 (0.52) | USP30LMNANPSR1UCHL1NPC1 | |
| SCHEMBL31515502 | 0.78 | LMNA (0.63) | USP30LMNANPSR1UCHL1NPC1 | |
| SCHEMBL18487506 | 0.78 | LMNA (0.63) | USP30LMNANPSR1UCHL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928127-B | Substituted piperidine amide derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-07-16 | — | — | CN | disclosed |