Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626727 | 0.89 | NAMPT (0.34) | KMT2AHTTALDH1A1MEN1HPGD | |
| SCHEMBL28626583 | 0.88 | HTT (0.39) | KMT2AHTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28636905 | 0.87 | GPR52 (0.34) | PTGS2ALDH1A1NAMPT | |
| SCHEMBL22899612 | 0.85 | SMN1; SMN2 (0.38) | KMT2AHTTALDH1A1NPC1RAB9A | |
| SCHEMBL29486220 | 0.85 | SMN1; SMN2 (0.38) | KMT2AHTTALDH1A1NPC1RAB9A | |
| SCHEMBL30511547 | 0.84 | SMN1; SMN2 (0.36) | KMT2AHTTALDH1A1NPC1RAB9A | |
| SCHEMBL21616999 | 0.84 | SMN1; SMN2 (0.36) | KMT2AHTTALDH1A1NPC1RAB9A | |
| SCHEMBL28922687 | 0.82 | IGF1R (0.36) | HTTALDH1A1NAMPTRXFP1F3 | |
| SCHEMBL31611960 | 0.82 | KMT2A (0.43) | KMT2AHTTALDH1A1NPC1RAB9A | |
| SCHEMBL21617101 | 0.82 | KMT2A (0.43) | KMT2AHTTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638876-A | phenyl/pyridyl-N-phenyl/pyridyl derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2021-04-09 | — | — | CN | disclosed |