Boric Acid

Boric Acid

SCHEMBL28618892

OB(O)O.OC(c1ccccc1)(c1ccccc1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2C9 P11712 2/20 0.42
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 3/20 0.41
TRPV6 Q9H1D0 3/20 0.41
TSHR P16473 2/20 0.41
ORAI1 Q96D31 2/20 0.41
ORAI2 Q96SN7 2/20 0.41
ORAI3 Q9BRQ5 2/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
ENPP2 Q13822 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
KCNN4 O15554 1/20 0.41
PCSK9 Q8NBP7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7173455 0.91 CYP1A2 (0.48) CYP2C19CYP1A2CYP2C9CYP3A4MAPK1
SCHEMBL36629 0.91 CYP1A2 (0.48) CYP2C19CYP1A2CYP2C9CYP3A4MAPK1
Boric Acid SCHEMBL28359306 0.82 TSHR (0.50) CYP2C19CYP1A2CYP2C9MAPK1TSHR
SCHEMBL7743285 0.81 CYP1A2 (0.46) CYP2C19CYP1A2CYP2C9CYP3A4MAPK1
Boric Acid SCHEMBL29150385 0.81 NR1H2 (0.50) CYP2C19CYP3A4MAPK1ALDH1A1TRPV6
Methoxymethane SCHEMBL2856857 0.80 KCNN4 (0.48) CYP2C19CYP1A2CYP2C9CYP3A4MAPK1
SCHEMBL982540 0.80 ALDH1A1 (0.42) CYP2C19CYP1A2CYP2C9CYP3A4MAPK1
SCHEMBL25220200 0.78 TSHR (0.43) CYP2C19CYP1A2CYP2C9CYP3A4MAPK1
SCHEMBL11511851 0.78 TSHR (0.61) CYP1A2MAPK1TRPV6TSHRORAI1
SCHEMBL2864477 0.78 TSHR (0.61) CYP1A2MAPK1TRPV6TSHRORAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874244-B Preparation method of aryl borate or alkyl borate compound 中国科学院兰州化学物理研究所 2023-12-01 CN disclosed
CN-116813821-A Nickel or palladium catalyst and preparation method and application thereof 中国科学院长春应用化学研究所 2023-09-29 CN disclosed
CN-113292582-B Synthesis and application of bifunctional fluorescent probe capable of distinguishing hydroxyl free radicals and hydrogen peroxide simultaneously 湖南师范大学 2022-04-15 CN disclosed
CN-113292582-A Synthesis and application of bifunctional fluorescent probe capable of distinguishing hydroxyl free radicals and hydrogen peroxide simultaneously 湖南师范大学 2021-08-24 CN disclosed
CN-111184877-B Nano contrast medium for electronic computer tomography imaging and preparation method thereof 同济大学 2021-08-06 CN disclosed
CN-111184877-A Nano contrast medium for electronic computer tomography imaging and preparation method thereof 同济大学 2020-05-22 CN disclosed