Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924661 | 1.00 | ACHE (0.44) | ACHEKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28619352 | 0.84 | ACHE (0.47) | ACHEKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16738816 | 0.84 | ACHE (0.49) | ACHEKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8170903 | 0.74 | ACHE (0.56) | ACHEKMT2AMEN1KDM4EMAPT | |
| SCHEMBL14939220 | 0.71 | CYP19A1 (0.59) | ACHEKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11379093 | 0.71 | ACHE (0.52) | ACHEKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL7731771 | 0.71 | ACHE (0.56) | ACHEKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL28804495 | 0.71 | ACHE (0.52) | ACHEKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL3276920 | 0.70 | METAP1 (0.44) | ACHEKMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28222973 | 0.70 | NPC1 (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307749-B | Method for synthesizing beta-ketosulfone derivative under mild condition and obtained beta-ketosulfone derivative | 佛山湘潭大学绿色智造研究院 | 2022-09-09 | — | — | CN | disclosed |
| CN-113307749-A | Method for synthesizing beta-ketosulfone derivative under mild condition and obtained beta-ketosulfone derivative | 佛山湘潭大学绿色智造研究院 | 2021-08-27 | — | — | CN | disclosed |