Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738816 | 0.87 | ACHE (0.49) | ACHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28222973 | 0.85 | NPC1 (0.49) | VDRLMNAPSEN1PSEN2APH1B | |
| SCHEMBL28619348 | 0.84 | ACHE (0.44) | ACHELMNAALDH1A1MAPTMETAP1 | |
| SCHEMBL29924661 | 0.84 | ACHE (0.44) | ACHELMNAALDH1A1MAPTMETAP1 | |
| SCHEMBL8170903 | 0.77 | ACHE (0.56) | ACHEMAPTMETAP1MEN1KMT2A | |
| SCHEMBL10806805 | 0.75 | VDR (0.48) | ACHEVDRLMNAPSEN1PSEN2 | |
| SCHEMBL28804495 | 0.74 | ACHE (0.52) | ACHEMAPTMETAP1MEN1KMT2A | |
| SCHEMBL11379093 | 0.74 | ACHE (0.52) | ACHEMAPTMETAP1MEN1KMT2A | |
| SCHEMBL7731771 | 0.74 | ACHE (0.56) | ACHEMAPTMETAP1MEN1KMT2A | |
| SCHEMBL316167 | 0.72 | MAPT (0.51) | ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307749-B | Method for synthesizing beta-ketosulfone derivative under mild condition and obtained beta-ketosulfone derivative | 佛山湘潭大学绿色智造研究院 | 2022-09-09 | — | — | CN | disclosed |
| CN-113307749-A | Method for synthesizing beta-ketosulfone derivative under mild condition and obtained beta-ketosulfone derivative | 佛山湘潭大学绿色智造研究院 | 2021-08-27 | — | — | CN | disclosed |