Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012855 | 0.85 | LMNA (0.46) | LMNATSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL7975753 | 0.80 | — | — | |
| SCHEMBL229792 | 0.80 | TSHR (0.50) | LMNATSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL181911 | 0.79 | LMNA (0.47) | LMNATSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL29467311 | 0.79 | LMNA (0.47) | LMNATSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL11133563 | 0.79 | LMNA (0.42) | LMNATSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL28875912 | 0.78 | LMNA (0.48) | LMNATSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL28727541 | 0.78 | LMNA (0.48) | LMNATSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL18152012 | 0.78 | LMNA (0.48) | LMNATSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL1037280 | 0.77 | FAAH (0.56) | LMNATSHRHSD17B10ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053479-B | Method for synthesizing quaternary amine inner salt | 兆科药业（合肥）有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-109053479-B | Method for synthesizing quaternary amine inner salt | 兆科药业（合肥）有限公司 | 2021-09-07 | — | — | CN | disclosed |