Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035745 | 0.78 | NSD2 (0.74) | KMT2AMEN1LMNATP53NSD2 | |
| SCHEMBL15569573 | 0.76 | NOTUM (0.53) | KMT2AMEN1TP53SMN1; SMN2NOTUM | |
| SCHEMBL8535957 | 0.74 | KMT2A (0.64) | KMT2AMEN1TP53SMN1; SMN2USP2 | |
| SCHEMBL20010538 | 0.73 | KMT2A (0.47) | KMT2ATP53SMN1; SMN2NOTUM | |
| SCHEMBL28611383 | 0.73 | CYP3A4 (0.50) | KMT2AMEN1NSD2MAPK1 | |
| SCHEMBL15825106 | 0.72 | KMT2A (0.71) | KMT2AMEN1LMNATP53SMN1; SMN2 | |
| SCHEMBL4324303 | 0.72 | SMN1; SMN2 (0.53) | KMT2AMEN1TP53SMN1; SMN2NOTUM | |
| SCHEMBL11579444 | 0.72 | NSD2 (0.67) | KMT2AMEN1NSD2SMN1; SMN2MAPK1 | |
| SCHEMBL6851163 | 0.71 | NSD2 (0.70) | KMT2AMEN1LMNATP53NSD2 | |
| SCHEMBL31175292 | 0.71 | SMN1; SMN2 (0.71) | KMT2AMEN1LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292728-A | Preparation method and application of polybenzimidazole polymer with high proton conductivity for fuel cell | 中国科学院上海有机化学研究所 | 2021-08-24 | — | — | CN | disclosed |