SCHEMBL15569573

SCHEMBL15569573

O=C(O)c1cc(C(=O)O)cc(-n2cnnn2)c1

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 3/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
KCNJ1 P48048 3/20 0.51
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.48
KMT2A Q03164 3/20 0.48
RAB9A P51151 1/20 0.46
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31401248 0.88 NOTUM (0.69) NOTUMSMN1; SMN2KCNJ1TP53MAPT
SCHEMBL20010538 0.85 KMT2A (0.47) NOTUMSMN1; SMN2KCNJ1TP53MAPT
SCHEMBL4324303 0.84 SMN1; SMN2 (0.53) NOTUMSMN1; SMN2KCNJ1TP53KMT2A
SCHEMBL31175292 0.82 SMN1; SMN2 (0.71) NOTUMSMN1; SMN2TP53KMT2ARAB9A
SCHEMBL14919351 0.82 SMN1; SMN2 (0.48) NOTUMSMN1; SMN2KCNJ1TP53MAPT
SCHEMBL939911 0.82 SMN1; SMN2 (0.71) NOTUMSMN1; SMN2TP53KMT2ARAB9A
SCHEMBL1072252 0.81 KCNJ1 (0.71) NOTUMSMN1; SMN2KCNJ1MAPTKMT2A
SCHEMBL2205346 0.81 NOTUM (0.54) NOTUMSMN1; SMN2KCNJ1TP53KMT2A
SCHEMBL4329216 0.81 KMT2A (0.51) NOTUMSMN1; SMN2KCNJ1TP53KMT2A
SCHEMBL357612 0.81 P2RY14 (0.50) NOTUMSMN1; SMN2KCNJ1TP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112573560-A Preparation method of high-dispersion zinc oxide 常州市五洲化工有限公司 2021-03-30 CN claimed
CN-114698647-A Zinc oxide/metal antibacterial powder and preparation method thereof 中氪新能源科技(上海)有限公司 2022-07-05 CN disclosed
CN-112573560-A Preparation method of high-dispersion zinc oxide 常州市五洲化工有限公司 2021-03-30 CN disclosed
CN-112573560-A Preparation method of high-dispersion zinc oxide 常州市五洲化工有限公司 2021-03-30 CN disclosed
US-10279334-B2 Microporous metal-organic frameworks for the removal of acetylene from ethylene THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-05-07 US disclosed
US-10279334-B2 Microporous metal-organic frameworks for the removal of acetylene from ethylene THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-05-07 US disclosed
US-10266737-B2 Adsorption systems using metal-organic frameworks ARKEMA INC. (US) 2019-04-23 US disclosed
US-20180085733-A1 MICROPOROUS METAL-ORGANIC FRAMEWORKS FOR THE REMOVAL OF ACETYLENE FROM ETHYLENE THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2018-03-29 US disclosed
US-20180085733-A1 MICROPOROUS METAL-ORGANIC FRAMEWORKS FOR THE REMOVAL OF ACETYLENE FROM ETHYLENE THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2018-03-29 US disclosed
WO-2016154300-A1 MICROPOROUS METAL-ORGANIC FRAMEWORKS FOR THE REMOVAL OF ACETYLENE FROM ETHYLENE THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-09-29 WO disclosed
US-20150291870-A1 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS ARKEMA INC. 2015-10-15 US disclosed
EP-2885365-A2 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS Arkema, Inc. (US) 2015-06-24 EP disclosed
WO-2014028574-A9 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS ARKEMA INC. (US) 2015-04-02 WO disclosed
WO-2014028574-A2 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS ARKEMA INC. (US) 2014-02-20 WO disclosed
CN-101531671-B Micro-porous copper coordination polymer, preparation method and application thereof UNIV NANKAI 2011-06-08 CN disclosed
CN-101531671-A Micro-porous copper coordination polymer, preparation method and application thereof UNIV NANKAI 2009-09-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180085733-A1 MICROPOROUS METAL-ORGANIC FRAMEWORKS FOR THE REMOVAL OF ACETYLENE FROM ETHYLENE AOC1, AOC2, SOD1 NOTUM 2379/4885SMN1; SMN2 4035/4885KCNJ1 1995/4885
US-20150291870-A1 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS PFAS, CHIA, PARN NOTUM 1537/4885SMN1; SMN2 4791/4885KCNJ1 746/4885
US-10279334-B2 Microporous metal-organic frameworks for the removal of acetylene from ethylene AOC1, AOC2, SOD1 NOTUM 2379/4885SMN1; SMN2 4035/4885KCNJ1 1995/4885
US-10266737-B2 Adsorption systems using metal-organic frameworks PFAS, CHIA, PARN NOTUM 1537/4885SMN1; SMN2 4791/4885KCNJ1 746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.