Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ATF4 | P18848 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152076 | 0.84 | KMT2A (0.56) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL8539679 | 0.83 | ALDH1A1 (0.55) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL16232250 | 0.83 | KCNJ1 (0.49) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL15017598 | 0.83 | KMT2A (0.55) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL18109145 | 0.81 | RAB9A (0.60) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL11851882 | 0.80 | RAB9A (0.68) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL6152072 | 0.79 | KMT2A (0.60) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL7684998 | 0.79 | ALDH1A1 (0.54) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL8063648 | 0.78 | ALDH1A1 (0.82) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL11832812 | 0.77 | KDM4E (0.56) | KMT2ARAB9AKDM4EMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884311-A2 | Triazole Derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1998-12-16 | — | — | EP | disclosed |