Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115838 | 0.92 | MEN1 (0.53) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL28918834 | 0.89 | PIN1 (0.43) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL17240946 | 0.85 | MEN1 (0.47) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL2115836 | 0.84 | PIN1 (0.47) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL2115841 | 0.84 | PIN1 (0.47) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL2115563 | 0.83 | ALDH1A1 (0.50) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL2115566 | 0.83 | ALDH1A1 (0.50) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL2609720 | 0.82 | MAPT (0.51) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL2115968 | 0.81 | PIN1 (0.45) | ALDH1A1PIN1TRPM8MEN1KMT2A | |
| SCHEMBL3213534 | 0.81 | ALDH1A1 (0.55) | ALDH1A1PIN1TRPM8SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115531366-A | Method of treating multiple sclerosis | 渤健马萨诸塞州股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115501218-A | Methods of treating multiple sclerosis | 渤健马萨诸塞州股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-113368093-A | Methods of treating multiple sclerosis | 比奥根玛公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-113368092-A | Methods of treating multiple sclerosis | 比奥根玛公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-113368091-A | Methods of treating multiple sclerosis | 比奥根玛公司 | 2021-09-10 | — | — | CN | disclosed |