Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 13/20 | 0.93 |
| ▸ | MAOB | P27338 | 13/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28886844 | 0.95 | MAOA (0.84) | MAOAMAOBKMT2APKMHTT | |
| SCHEMBL28623824 | 0.90 | MAOA (0.75) | MAOAMAOBKMT2APKMHTT | |
| SCHEMBL28629790 | 0.89 | MAOA (0.74) | MAOAMAOBKMT2APKMHTT | |
| SCHEMBL28615788 | 0.85 | MAOB (0.69) | MAOAMAOBKMT2APKMHTT | |
| SCHEMBL28625191 | 0.85 | MAOA (0.69) | MAOAMAOBKMT2APKMHTT | |
| SCHEMBL28634494 | 0.84 | TSHR (0.74) | MAOAMAOBKMT2APKMHTT | |
| SCHEMBL28921780 | 0.82 | MAOA (0.65) | MAOAMAOBKMT2APKMSMN1; SMN2 | |
| SCHEMBL28622147 | 0.81 | MAOA (0.70) | MAOAMAOBKMT2APKMSMN1; SMN2 | |
| SCHEMBL29987280 | 0.80 | MAOA (0.61) | MAOAMAOBKMT2APKMSMN1; SMN2 | |
| SCHEMBL19994563 | 0.79 | MAOB (1.00) | MAOAMAOBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354646-B | 8-aryloxy alkoxy substituted xanthine derivative and preparation method and application thereof | 南开大学 | 2022-11-15 | — | — | CN | claimed |
| CN-113354646-A | 8-aryloxy alkoxy substituted xanthine derivative and preparation method and application thereof | 南开大学 | 2021-09-07 | — | — | CN | claimed |
| CN-113354646-B | 8-aryloxy alkoxy substituted xanthine derivative and preparation method and application thereof | 南开大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-113354646-A | 8-aryloxy alkoxy substituted xanthine derivative and preparation method and application thereof | 南开大学 | 2021-09-07 | — | — | CN | disclosed |