Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.70 |
| ▸ | MAOB | P27338 | 14/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540042 | 0.91 | MAOA (0.70) | MAOAMAOBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11150726 | 0.83 | SMN1; SMN2 (0.97) | MAOAMAOBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28619948 | 0.81 | MAOA (0.93) | MAOAMAOBSMN1; SMN2KMT2APKM | |
| SCHEMBL33834 | 0.80 | KMT2A (0.70) | MAOAMAOBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28629790 | 0.80 | MAOA (0.74) | MAOAMAOBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6454391 | 0.80 | MAOA (0.67) | MAOAMAOBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14028301 | 0.79 | MAOA (0.93) | MAOAMAOBSMN1; SMN2KMT2APKM | |
| SCHEMBL28921780 | 0.79 | MAOA (0.65) | MAOAMAOBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11151123 | 0.79 | SMN1; SMN2 (0.68) | MAOAMAOBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28634494 | 0.78 | TSHR (0.74) | MAOAMAOBSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354646-B | 8-aryloxy alkoxy substituted xanthine derivative and preparation method and application thereof | 南开大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-113354646-A | 8-aryloxy alkoxy substituted xanthine derivative and preparation method and application thereof | 南开大学 | 2021-09-07 | — | — | CN | disclosed |