SCHEMBL28620104

SCHEMBL28620104

NOB(ON)c1ccccc1N.[Pt]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.41
ALOX15 P16050 2/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 6/20 0.36
TDP1 Q9NUW8 3/20 0.34
ADRA2B P18089 1/20 0.34
PTGS1 P23219 1/20 0.34
KEAP1 Q14145 2/20 0.34
TSHR P16473 4/20 0.33
ADRA2C P18825 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28360418 0.98 CYP3A4 (0.43) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Hydrochloric Acid SCHEMBL28507710 0.95 CYP3A4 (0.41) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Water SCHEMBL28854478 0.95 CYP3A4 (0.41) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL12424043 0.76 ALDH1A1 (0.44) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL20312366 0.71 CYP3A4 (0.36) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL10233523 0.67 CYP3A4 (0.47) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL56105 0.67 CYP3A4 (0.47) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL29780861 0.67 CYP3A4 (0.47) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL13215265 0.67 CYP3A4 (0.47) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL11772780 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109540983-B Novel electrochemical biosensor for detecting alpha 2,6 sialylated glycans 重庆医科大学 2021-09-03 CN claimed
CN-109540983-B Novel electrochemical biosensor for detecting alpha 2,6 sialylated glycans 重庆医科大学 2021-09-03 CN disclosed