Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615232 | 0.86 | LMNA (0.43) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28624008 | 0.86 | LMNA (0.43) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28616025 | 0.84 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28620632 | 0.84 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28627378 | 0.83 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28619465 | 0.83 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL6094022 | 0.82 | CCR6 (0.51) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL29690625 | 0.82 | CCR6 (0.51) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL29690580 | 0.82 | CCR6 (0.51) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28629974 | 0.82 | KDM4E (0.44) | LMNACCR6HKDC1HTTIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200967-B | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113200967-A | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2021-08-03 | — | — | CN | disclosed |