Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624008 | 0.95 | LMNA (0.43) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28616025 | 0.87 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28619465 | 0.86 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28620116 | 0.86 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28620632 | 0.82 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL28624019 | 0.81 | VDR (0.45) | LMNAHTTKDM4EMEN1ALDH1A1 | |
| SCHEMBL28627378 | 0.81 | LMNA (0.49) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL6094022 | 0.76 | CCR6 (0.51) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL29690580 | 0.76 | CCR6 (0.51) | LMNACCR6HKDC1HTTIMPDH2 | |
| SCHEMBL29690625 | 0.76 | CCR6 (0.51) | LMNACCR6HKDC1HTTIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200967-B | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113200967-A | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2021-08-03 | — | — | CN | disclosed |