SCHEMBL28620191

SCHEMBL28620191

O=c1ccc2cc(Cl)ccc2o1.[Co]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.58
CA9 Q16790 5/20 0.58
ALDH1A1 P00352 3/20 0.58
MCL1 Q07820 3/20 0.58
ACHE P22303 2/20 0.56
MAOB P27338 1/20 0.56
LMNA P02545 3/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP3A4 P08684 2/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
ALOX15 P16050 2/20 0.55
HIF1A Q16665 2/20 0.55
HSD17B10 Q99714 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
GMNN O75496 1/20 0.55
TP53 P04637 1/20 0.55
CYP2D6 P10635 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3086551 0.98 CA12 (0.60) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL28918561 0.91 ACHE (0.56) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL28918564 0.91 CA12 (0.58) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL17294126 0.85 PGR (0.55) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL7022121 0.85 MAOB (0.50) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL11036186 0.83 CA12 (0.59) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL5542275 0.75 CA12 (0.62) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL15842745 0.75 CA9 (0.59) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL6774085 0.74 CA12 (0.56) CA12CA9ALDH1A1MCL1ACHE
SCHEMBL16410056 0.73 CA12 (0.60) CA12CA9ALDH1A1MCL1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113307831-B Preparation method and application of cobalt (II) coumarin Schiff base complex 安徽工业大学 2023-08-22 CN claimed
CN-113307831-A Preparation method and application of cobalt (II) coumarin Schiff base complex 安徽工业大学 2021-08-27 CN claimed
CN-113307831-B Preparation method and application of cobalt (II) coumarin Schiff base complex 安徽工业大学 2023-08-22 CN disclosed
CN-113307831-A Preparation method and application of cobalt (II) coumarin Schiff base complex 安徽工业大学 2021-08-27 CN disclosed