Naphthylamine

Naphthylamine

SCHEMBL28620262

N=C(N)NCCCC(NC(=O)c1ccccc1)C(=O)O.Nc1ccc2ccccc2c1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.44
C3AR1 Q16581 5/20 0.43
PIN1 Q13526 5/20 0.43
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
PADI6 Q6TGC4 1/20 0.42
PADI1 Q9ULC6 1/20 0.42
PADI3 Q9ULW8 1/20 0.42
PADI4 Q9UM07 1/20 0.42
PADI2 Q9Y2J8 1/20 0.42
TGM2 P21980 2/20 0.41
DHFR P00374 1/20 0.41
SIRT5 Q9NXA8 1/20 0.40
FOLH1 Q04609 2/20 0.40
MCHR1 Q99705 1/20 0.40
MC4R P32245 1/20 0.40
MC3R P41968 1/20 0.40
MC1R Q01726 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthylamine SCHEMBL28869561 0.99 CA2 (0.43) CA2C3AR1PIN1PDE4APDE4B
Naphthalene SCHEMBL28216957 0.91 C3AR1 (0.49) CA2C3AR1PDE4APDE4BPDE4C
SCHEMBL28693057 0.90 PIN1 (0.47) CA2C3AR1PIN1PDE4APDE4B
Naphthylamine SCHEMBL27915557 0.88 C3AR1 (0.46) C3AR1PIN1TGM2SIRT5FOLH1
SCHEMBL7925397 0.88 C3AR1 (0.52) CA2C3AR1PDE4APDE4BPDE4C
SCHEMBL188589 0.88 C3AR1 (0.52) CA2C3AR1PDE4APDE4BPDE4C
SCHEMBL188590 0.88 C3AR1 (0.52) CA2C3AR1PDE4APDE4BPDE4C
Naphthylamine SCHEMBL28084554 0.87 NPY4R (0.44) C3AR1TGM2SIRT5MC4RMC3R
SCHEMBL25158952 0.85 FOLH1 (0.48) CA2C3AR1FOLH1
SCHEMBL5892488 0.85 FOLH1 (0.48) CA2C3AR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107090486-B Articles and methods for detecting target microorganisms 3M创新有限公司 2021-09-03 CN disclosed