Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | CD38 | P28907 | 15/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088047 | 0.74 | PRKCD (0.59) | DYRK1ACD38KDRMAPT | |
| SCHEMBL19219055 | 0.72 | PIM1 (0.51) | DYRK1ACD38DYRK2DYRK1BMAPT | |
| SCHEMBL27835195 | 0.72 | PRKCD (0.50) | KDRMAPT | |
| SCHEMBL2722754 | 0.72 | DYRK1A (0.77) | DYRK1ACD38DYRK2DYRK1BMAPT | |
| SCHEMBL16205256 | 0.72 | CD38 (0.60) | DYRK1ACD38KDRRETMAPT | |
| SCHEMBL48894 | 0.72 | DYRK1A (0.55) | DYRK1ACD38KDRDYRK2DYRK1B | |
| SCHEMBL1872880 | 0.72 | DYRK1A (0.55) | DYRK1ACD38DYRK2DYRK1BMAPT | |
| SCHEMBL27720410 | 0.71 | KDR (0.49) | KDRMAPT | |
| SCHEMBL1120968 | 0.70 | AURKA (0.42) | KDRMAPT | |
| SCHEMBL19219067 | 0.70 | DYRK1A (0.53) | DYRK1ACD38KDRDYRK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368129-B | Modified macrocyclic compounds | 拜耳医药股份有限公司 | 2021-08-17 | — | — | CN | disclosed |