Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231091 | 0.96 | FDPS (0.56) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL31312939 | 0.83 | HRH1 (0.54) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1971651 | 0.82 | HRH1 (0.46) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5556933 | 0.80 | HRH1 (0.47) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL28265938 | 0.79 | HRH1 (0.50) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7003387 | 0.79 | HRH1 (0.50) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL3902944 | 0.79 | HRH1 (0.50) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7123795 | 0.79 | HRH1 (0.55) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL4262034 | 0.78 | HRH1 (0.48) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1462070 | 0.78 | HRH1 (0.53) | FDPSHRH1SMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942220-B | Preparation method of salt-resistant amphoteric polycarboxylic acid high-performance water reducing agent | 北京工业大学 | 2021-07-23 | — | — | CN | claimed |
| CN-109942220-B | Preparation method of salt-resistant amphoteric polycarboxylic acid high-performance water reducing agent | 北京工业大学 | 2021-07-23 | — | — | CN | disclosed |