SCHEMBL5556933

SCHEMBL5556933

NC(Cc1ccccn1)(c1ccccn1)c1ccccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.47
FDPS P14324 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
MAPT P10636 1/20 0.41
LIN28A Q9H9Z2 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
PRMT1 Q99873 1/20 0.41
PTPRA P18433 1/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231091 0.84 FDPS (0.56) HRH1FDPSSMN1; SMN2L3MBTL1MAOA
SCHEMBL28054527 0.82 HRH1 (0.48) HRH1FDPSSMN1; SMN2L3MBTL1MAOA
SCHEMBL5671888 0.81 HRH1 (0.53) HRH1SMN1; SMN2L3MBTL1KMT2ANPC1
SCHEMBL7559371 0.81 SMN1; SMN2 (0.45) SMN1; SMN2L3MBTL1KDM4EALDH1A1HSD17B10
Bromide SCHEMBL28620601 0.80 FDPS (0.53) HRH1FDPSSMN1; SMN2L3MBTL1MAOA
SCHEMBL31312939 0.79 HRH1 (0.54) HRH1FDPSSMN1; SMN2L3MBTL1MAOA
SCHEMBL7838478 0.78 SMN1; SMN2 (0.42) FDPSSMN1; SMN2L3MBTL1TDP1
SCHEMBL15551933 0.78 SMN1; SMN2 (0.50) HRH1SMN1; SMN2L3MBTL1MAPTTDP1
SCHEMBL27718690 0.78 HRH1 (0.41) HRH1FDPSSMN1; SMN2L3MBTL1MAOA
SCHEMBL19916541 0.77 FDPS (0.46) HRH1FDPSSMN1; SMN2L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3818101-A1 LIQUIDS Borchers Catalyst (UK) Limited (GB) 2021-05-12 EP disclosed
WO-2020008203-A1 LIQUIDS CATEXEL LIMITED (GB) 2020-01-09 WO disclosed
EP-3390486-A1 OXIDATIVELY CURABLE COATING COMPOSITION Catexel Limited (GB) 2018-10-24 EP disclosed
EP-3307940-A1 OXIDATIVE METHOD Catexel Technologies Limited (GB) 2018-04-18 EP disclosed
WO-2017103620-A1 OXIDATIVELY CURABLE COATING COMPOSITION CATEXEL LIMITED (GB) 2017-06-22 WO disclosed
WO-2016198890-A1 OXIDATIVE METHOD CHEMSENTI LIMITED (GB) 2016-12-15 WO disclosed
EP-1341893-B1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER NV (NL) 2007-05-02 EP disclosed
US-20020013246-A1 Composition and method for bleaching laundry fabrics UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-31 US disclosed
US-20020010121-A1 Bleaching and dye transfer inhibiting composition and method for laundry fabrics UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-24 US disclosed
EP-1109965-A1 METHOD OF TREATING A TEXTILE UNILEVER PLC (GB) 2001-06-27 EP disclosed
EP-1109884-A1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2001-06-27 EP disclosed
WO-2000012808-A1 METHOD OF TREATING A TEXTILE UNILEVER PLC (GB) 2000-03-09 WO disclosed
WO-2000012667-A1 COMPOSITION AND METHOD FOR BLEACHING A SUBSTRATE UNILEVER PLC (GB) 2000-03-09 WO disclosed