Juarezic Acid

Juarezic Acid

SCHEMBL28620644

C=CC#N.O=C(O)C=CC=Cc1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC10 Q969S8 2/20 0.43
HDAC11 Q96DB2 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
HDAC5 Q9UQL6 2/20 0.43
TNKS O95271 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
MAOB P27338 5/20 0.41
MAPT P10636 4/20 0.41
ALDH1A1 P00352 3/20 0.41
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juarezic Acid SCHEMBL64796 0.89 HDAC3 (0.53) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL377920 0.89 HDAC3 (0.53) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL7761086 0.86 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL2246623 0.86 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL27767651 0.85 HDAC3 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
Maleic Anhydride SCHEMBL28856601 0.85 MAOB (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
Juarezic Acid SCHEMBL15064809 0.83 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
Maleic Anhydride SCHEMBL148559 0.79 MAOB (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2
Styrene SCHEMBL6429706 0.78 ALDH1A1 (0.48) MAPTALDH1A1MCL1LMNAHTT
Maleic Anhydride SCHEMBL10691759 0.78 MAOB (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107771198-B Method for producing fiber composite material by using amorphous chemically modified polymer with reinforced fiber 英力士苯领集团股份公司 2021-08-24 CN disclosed
CN-107709416-B Production of fibrous composites using amorphous chemically modified polymers 英力士苯领集团股份公司 2021-08-24 CN disclosed