Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Z)-1,2-Diphenylethene SCHEMBL23274191 | 0.91 | MAOB (0.46) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| (Z)-1,2-Diphenylethene SCHEMBL23274192 | 0.91 | MAOB (0.46) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| Maleic Anhydride SCHEMBL1802308 | 0.89 | MAOB (0.48) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| Maleic Anhydride SCHEMBL27692804 | 0.88 | MAOB (0.46) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| Juarezic Acid SCHEMBL377920 | 0.88 | HDAC3 (0.53) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| Maleic Anhydride SCHEMBL148559 | 0.86 | MAOB (0.45) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| Maleic Anhydride SCHEMBL27994783 | 0.85 | HDAC3 (0.50) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| Maleic Anhydride SCHEMBL1091519 | 0.83 | LMNA (0.40) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| Maleic Anhydride SCHEMBL9101172 | 0.83 | LMNA (0.40) | MAOBALDH1A1LMNAMAPK1TRPA1 | |
| Maleic Anhydride SCHEMBL28856601 | 0.81 | MAOB (0.40) | MAOBALDH1A1LMNAMAPK1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753997-A | FREE RADICAL PEROXIDE INITIATOR, TERIARY AMINE CATALYST WITH OXYGEN, NITROGEN OR SULFUR MOIETIES | THE STANDARD OIL COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0225186-A2 | Process for grafting maleic anhydride or styrene-maleic anhydride onto polyolefins | THE STANDARD OIL COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |