Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430647 | 1.00 | LMNA (0.58) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL28631447 | 0.85 | LMNA (0.68) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL30431173 | 0.85 | LMNA (0.68) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL28616516 | 0.80 | ALDH1A1 (0.73) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL30431609 | 0.80 | ALDH1A1 (0.73) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL28619635 | 0.79 | EPAS1 (0.71) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL30431601 | 0.79 | EPAS1 (0.71) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL30430973 | 0.76 | ALDH1A1 (0.63) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL28620603 | 0.76 | ALDH1A1 (0.63) | LMNAMEN1KMT2AHSD17B10GAA | |
| SCHEMBL8976661 | 0.72 | ALDH1A1 (0.77) | LMNAMEN1KMT2AHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264900-A | Preparation method and medical application of benzisothiazole and benzothiophene | 南京中医药大学 | 2021-08-17 | — | — | CN | claimed |
| CN-113264900-B | Preparation method and medical application of benzisothiazole and benzothiophene | 南京中医药大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-113264900-A | Preparation method and medical application of benzisothiazole and benzothiophene | 南京中医药大学 | 2021-08-17 | — | — | CN | disclosed |