SCHEMBL28622014

SCHEMBL28622014

CCC(C)(CN)c1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
KIF11 P52732 5/20 0.39
PRKCQ Q04759 4/20 0.39
TAAR1 Q96RJ0 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2A6 P11509 1/20 0.37
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
ACHE P22303 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19981757 0.86 TSHR (0.55) TSHRESR1ESR2CA1CA2
SCHEMBL18432431 0.83 KIF11 (0.44) TSHRESR1ESR2CA1CA2
SCHEMBL29328154 0.81 ESR1 (0.40) ESR1ESR2KIF11PRKCQTAAR1
SCHEMBL1639986 0.81 ESR1 (0.63) TSHRESR1ESR2HPGD
SCHEMBL9064223 0.78 TSHR (0.46) TSHRESR1ESR2CA1CA2
SCHEMBL22912356 0.78 TSHR (0.46) TSHRESR1ESR2CA1CA2
SCHEMBL14390315 0.78 TSHR (0.41) TSHRESR1ESR2CA1CA2
SCHEMBL14390394 0.78 TSHR (0.41) TSHRCA1CA2CA5ACA9
SCHEMBL14390252 0.78 TSHR (0.41) TSHRESR1ESR2CA1CA2
SCHEMBL28629680 0.76 KIF11 (0.46) KIF11PRKCQTAAR1ACHEHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304075-B NON molecular sieve, preparation method and application thereof 中国石油化工股份有限公司 2023-08-08 CN disclosed
CN-115304075-A NON molecular sieve, preparation method and application thereof 中国石油化工股份有限公司 2022-11-08 CN disclosed
CN-112573534-B NON type molecular sieve and preparation method and application thereof 中国石油化工股份有限公司 2022-07-12 CN disclosed
CN-112573534-A NON type molecular sieve and preparation method and application thereof 中国石油化工股份有限公司 2021-03-30 CN disclosed