SCHEMBL22912356

SCHEMBL22912356

CCC(C)(CCl)c1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
ESR1 P03372 4/20 0.41
ESR2 Q92731 4/20 0.41
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MAPT P10636 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA5A P35218 1/20 0.35
CA9 Q16790 1/20 0.35
ACHE P22303 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
KIF11 P52732 4/20 0.34
HPGD P15428 1/20 0.34
AR P10275 1/20 0.32
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19981757 0.86 TSHR (0.55) TSHRESR1ESR2NPC1RAB9A
SCHEMBL3218267 0.81 ESR1 (0.63) TSHRESR1ESR2HPGDAR
SCHEMBL17710390 0.80 CYP2C19 (0.47) TSHRESR1ESR2MAPTALDH1A1
SCHEMBL28622014 0.78 TSHR (0.46) TSHRESR1ESR2NPC1RAB9A
SCHEMBL9064223 0.78 TSHR (0.46) TSHRESR1ESR2NPC1RAB9A
SCHEMBL28379090 0.77 ESR1 (0.36) ESR1ESR2MAPTALDH1A1
SCHEMBL15084185 0.75 TSHR (0.43) TSHRESR1ESR2NPC1RAB9A
SCHEMBL18432431 0.75 KIF11 (0.44) TSHRESR1ESR2NPC1RAB9A
SCHEMBL13930892 0.75 MAPT (0.50) TSHRESR1ESR2NPC1RAB9A
SCHEMBL12942968 0.75 MAPT (0.50) TSHRESR1ESR2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787880-B2 Highly soluble alkyl substituted carbenium borate as co-catalysts for olefin polymerizations DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-17 US disclosed
US-20210017305-A1 HIGHLY SOLUBLE ALKYL SUBSTITUTED CARBENIUM BORATE AS CO-CATALYSTS FOR OLEFIN POLYMERIZATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210017305-A1 HIGHLY SOLUBLE ALKYL SUBSTITUTED CARBENIUM BORATE AS CO-CATALYSTS FOR OLEFIN POLYMERIZATIONS YAP1, MCM4, COPS4 TSHR 4730/4885ESR1 706/4885ESR2 2823/4885
US-11787880-B2 Highly soluble alkyl substituted carbenium borate as co-catalysts for olefin polymerizations YAP1, MCM4, COPS4 TSHR 4730/4885ESR1 706/4885ESR2 2823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.