Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 4/20 | 0.50 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.30 |
| ▸ | HTR2B | P41595 | 3/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28987799 | 0.86 | GABRR1 (0.48) | GABRR1GABRR2PLGPLATLMNA | |
| SCHEMBL19032979 | 0.81 | SLC6A12 (0.52) | GABRR1GABRR2PLGPLATLMNA | |
| Fumaric Acid SCHEMBL28987793 | 0.81 | TSHR (0.45) | GABRR1GABRR2PLGPLATLMNA | |
| SCHEMBL8423168 | 0.80 | — | — | |
| SCHEMBL1649846 | 0.80 | — | — | |
| SCHEMBL15710033 | 0.80 | — | — | |
| Bicarbonate SCHEMBL31059126 | 0.80 | GABRR1 (0.48) | GABRR1GABRR2PLGPLATLMNA | |
| Trifluoroacetic Acid SCHEMBL28987800 | 0.79 | GABRR1 (0.43) | GABRR1GABRR2PLGPLATLMNA | |
| Oxalic Acid SCHEMBL9779895 | 0.78 | GABRR1 (0.41) | GABRR1GABRR2PLGPLATLMNA | |
| SCHEMBL9632104 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835570-A | Synthesis method of trans-1, 2-diaminomethyl-cyclobutane and salt thereof | 上海寻科生物医药科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-113416150-B | Synthetic method of lobaplatin intermediate | 上海寻科生物医药科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-113416150-A | Novel synthesis method of lobaplatin intermediate | 上海寻科生物医药科技有限公司 | 2021-09-21 | — | — | CN | disclosed |