Benzofuran

Benzofuran

SCHEMBL28622200

c1ccc(COCc2ccccc2)cc1.c1ccc2occc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
MAOB P27338 3/20 0.45
MAOA P21397 1/20 0.41
KCNA3 P22001 3/20 0.40
KCNA5 P22460 3/20 0.40
KCNA1 Q09470 1/20 0.40
MRGPRX4 Q96LA9 2/20 0.40
DAO P14920 1/20 0.40
HTR2B P41595 1/20 0.39
IDO1 P14902 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
ALOX5 P09917 1/20 0.38
CTNNB1 P35222 1/20 0.37
WNT3A P56704 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31681671 0.82 MAOB (0.44) MAOBMAOAIDO1LMNACTNNB1
Benzofuran SCHEMBL22129287 0.82 MAOB (0.44) MAOBMAOAIDO1LMNACTNNB1
Benzofuran SCHEMBL5564 0.79
Benzofuran SCHEMBL29415475 0.79
Benzofuran SCHEMBL5834531 0.79 MAOA (0.46) MAOBMAOAIDO1LMNACTNNB1
Benzofuran SCHEMBL29393518 0.79
Benzofuran SCHEMBL3160534 0.79
Benzofuran SCHEMBL28622198 0.79 TSHR (0.54) TSHRMAOBMAOAMRGPRX4IDO1
Biphenyl SCHEMBL9641251 0.78 ALDH1A1 (0.45) MAOBMAOAIDO1LMNACTNNB1
Benzofuran SCHEMBL1129070 0.77 MAOA (0.44) MAOBMAOAIDO1LMNACTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113164365-A Composition for inhibiting alopecia or skin inflammation 株式会社爱茉莉太平洋 2021-07-23 CN disclosed