Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18159251 | 0.82 | HRH3 (0.55) | HRH3HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL28613043 | 0.81 | KDM4E (0.62) | HRH3ALDH1A1LMNAMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28185355 | 0.79 | HRH3 (0.64) | HRH3HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL16293628 | 0.79 | HRH3 (0.64) | HRH3HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL10556415 | 0.79 | POLB (0.62) | HRH3HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL10554521 | 0.78 | POLB (0.61) | HRH3HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL10554135 | 0.78 | POLB (0.61) | HRH3HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL28910998 | 0.77 | ALDH1A1 (0.50) | HTR1AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28538209 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KCNJ1LMNAMEN1KMT2A | |
| SCHEMBL2228868 | 0.76 | ALDH1A1 (0.58) | HRH3HTR1ADRD2HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107400092-B | Pyrimidine derivative, preparation method thereof and application thereof in medicine | 浙江海正药业股份有限公司 | 2021-08-24 | — | — | CN | disclosed |