Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 4/20 | 0.50 |
| ▸ | CCND1 | P24385 | 4/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28621872 | 1.00 | MAPT (0.52) | MAPTKMT2AKDM4EGAPDHCDK4 | |
| SCHEMBL28922558 | 0.87 | KDM4E (0.55) | MAPTKDM4EALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL28635512 | 0.84 | ALDH1A1 (0.46) | MAPTKMT2AKDM4ELMNATDP1 | |
| SCHEMBL28631506 | 0.82 | SMN1; SMN2 (0.47) | MAPTKDM4EALDH1A1TP53MAPK13 | |
| SCHEMBL28624647 | 0.81 | KDM4E (0.46) | KMT2AKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL28622808 | 0.81 | CA1 (0.56) | MAPTKDM4ECDK2ALDH1A1MAPK1 | |
| SCHEMBL28623275 | 0.81 | CA1 (0.56) | MAPTKDM4ECDK2ALDH1A1MAPK1 | |
| SCHEMBL8020401 | 0.80 | MAPT (0.67) | MAPTKMT2AKDM4EGAPDHCDK4 | |
| SCHEMBL28102260 | 0.78 | MAPT (0.56) | MAPTKMT2AKDM4EGAPDHCDK4 | |
| SCHEMBL28102385 | 0.78 | MAPT (0.56) | MAPTKMT2AKDM4EGAPDHCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372275-B | Synthetic method of 3, 5-diaryl-4-trifluoromethyl pyrazole derivative | 温州大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-113372275-A | Synthetic method of 3, 5-diaryl-4-trifluoromethyl pyrazole derivative | 温州大学 | 2021-09-10 | — | — | CN | disclosed |