Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | CPS1 | P31327 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607569 | 0.81 | STS (0.45) | STSDDB1CRBNKMT2AMEN1 | |
| SCHEMBL28610512 | 0.80 | STS (0.56) | STSDDB1CRBNKMT2AMEN1 | |
| SCHEMBL28622743 | 0.78 | STS (0.52) | STSDDB1CRBNKMT2AMEN1 | |
| SCHEMBL28611806 | 0.78 | STS (0.52) | STSDDB1CRBNKMT2AMEN1 | |
| SCHEMBL27415228 | 0.73 | TSHR (0.55) | STSKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL30984098 | 0.73 | STS (0.53) | STSKMT2AMEN1ALDH1A1GPR119 | |
| SCHEMBL31242595 | 0.73 | HSD17B10 (0.39) | DDB1CRBNHPGD | |
| SCHEMBL31085659 | 0.69 | HSD11B1 (0.40) | HPGD | |
| SCHEMBL4573259 | 0.69 | SUV39H2 (0.48) | STSKMT2AMEN1ALDH1A1GPR119 | |
| SCHEMBL8108230 | 0.69 | SUV39H2 (0.48) | STSKMT2AMEN1ALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |