SCHEMBL2862348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3608292	0.89	PDE2A (0.44)	PDE2AHTR2AHTR2CHTR2BCES2
	SCHEMBL2855658	0.86	HTR2A (0.41)	PDE2AHTR2AHTR2CHTR2BCES2
	SCHEMBL12944872	0.80	MC4R (0.40)	HTR2CHTR2BMAPTL3MBTL1MC4R
	SCHEMBL2861151	0.78	PDE2A (0.41)	PDE2ACES2TAS1R3TAS1R1EPHX1
	SCHEMBL14121399	0.78	PDE2A (0.43)	PDE2AHTR2AHTR2CHTR2BCES2
	SCHEMBL2882405	0.78	PDE2A (0.43)	PDE2AHTR2AHTR2CHTR2BCES2
	SCHEMBL14121100	0.78	PDE2A (0.43)	PDE2AHTR2AHTR2CHTR2BCES2
	SCHEMBL2856708	0.76	PSEN1 (0.45)	PDE2ACES2TAS1R3TAS1R1EPHX1
	SCHEMBL34475260	0.76	CES2 (0.41)	PDE2ACES2MAPTL3MBTL1DPP7
	SCHEMBL3602797	0.74	PDE2A (0.43)	PDE2AMC4RSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.