SCHEMBL2856708

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2867471	0.85	TAS1R3 (0.42)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL6475583	0.82	PSEN1 (0.47)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL6472308	0.82	PSEN1 (0.47)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL29603116	0.79	CES2 (0.40)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL27643643	0.78	CES2 (0.47)	CES2POLQPDE2ACYP1A2CYP2C9
	SCHEMBL30427999	0.77	CES2 (0.50)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL4037426	0.77	PSEN1 (0.55)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL2861151	0.77	PDE2A (0.41)	CES2TAS1R3TAS1R1FFAR1PDE2A
	SCHEMBL2862348	0.76	PDE2A (0.40)	CES2TAS1R3TAS1R1PDE2AEPHX1
	SCHEMBL5170515	0.76	AKR1C3 (0.42)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.