SCHEMBL28623712

SCHEMBL28623712

Cc1c(Cl)c(O)cc(O)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.46
HSD17B10 Q99714 7/20 0.46
CYP3A4 P08684 6/20 0.46
TSHR P16473 5/20 0.46
ALOX15 P16050 2/20 0.46
HSP90AA1 P07900 1/20 0.46
CHRM1 P11229 1/20 0.46
MAOA P21397 1/20 0.46
TBXA2R P21731 1/20 0.46
ADRA1A P35348 1/20 0.46
HTR2B P41595 1/20 0.46
ALDH1A1 P00352 3/20 0.44
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
ACHE P22303 1/20 0.43
ACLY P53396 3/20 0.39
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dichloroxylenol SCHEMBL574277 0.86 ALDH1A1 (0.61) HPGDHSD17B10CYP3A4TSHRALOX15
Dichloroxylenol SCHEMBL29367847 0.86 ALDH1A1 (0.61) HPGDHSD17B10CYP3A4TSHRALOX15
SCHEMBL10592132 0.86 HSD17B10 (0.59) HPGDHSD17B10CYP3A4TSHRALOX15
Dichloroxylenol SCHEMBL28046030 0.84 ALDH1A1 (0.59) HPGDHSD17B10CYP3A4TSHRALOX15
SCHEMBL23205867 0.82 ALDH1A1 (0.38) HPGDHSD17B10CYP3A4TSHRALOX15
SCHEMBL10820980 0.80 ALDH1A1 (0.50) HPGDHSD17B10CYP3A4TSHRALOX15
SCHEMBL10935944 0.80 HSD17B10 (0.52) HPGDHSD17B10CYP3A4TSHRALOX15
SCHEMBL1286188 0.78 MAPT (0.48) HPGDHSD17B10CYP3A4TSHRALOX15
SCHEMBL11311046 0.78 ALOX15 (0.41) HPGDHSD17B10CYP3A4TSHRALOX15
SCHEMBL16072316 0.78 CYP3A4 (0.41) CYP3A4TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115381813-A Application of flavonoid compounds in preparation of diabetes prevention and treatment medicines 海南师范大学 2022-11-25 CN disclosed
CN-113350332-B Medicine for preventing and treating diabetes and application thereof 海南师范大学 2022-09-06 CN disclosed
CN-113350332-A Medicine for preventing and treating diabetes and application thereof 海南师范大学 2021-09-07 CN disclosed