SCHEMBL28623749

SCHEMBL28623749

COC1=CCC=C(OC)C1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.52
MAPT P10636 3/20 0.52
HKDC1 Q2TB90 2/20 0.52
TP53 P04637 2/20 0.52
CYP3A4 P08684 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MAPK1 P28482 2/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
KMT2A Q03164 1/20 0.52
TYR P14679 1/20 0.48
ALOX5 P09917 2/20 0.38
PTGS2 P35354 2/20 0.38
ERBB2 P04626 1/20 0.37
CDC25A P30304 4/20 0.35
CDC25B P30305 4/20 0.35
PTPN1 P18031 1/20 0.35
IDO1 P14902 1/20 0.35
RAB9A P51151 2/20 0.33
MAP2K7 O14733 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677824 0.82
SCHEMBL15020363 0.70
SCHEMBL197028 0.69 HKDC1 (0.70) KDM4EMAPTHKDC1TP53CYP3A4
2,6-Dimethoxyquinone SCHEMBL570683 0.69 HKDC1 (1.00) KDM4EMAPTHKDC1TP53CYP3A4
SCHEMBL29684687 0.65 TYR (1.00) KDM4EMAPTHKDC1TP53CYP3A4
SCHEMBL634177 0.65
SCHEMBL10824988 0.65 HKDC1 (0.64) KDM4EMAPTHKDC1TP53CYP3A4
SCHEMBL19957489 0.63 KDM4E (0.48) KDM4EMAPTHKDC1TP53CYP3A4
SCHEMBL8265788 0.63 CYP3A4 (0.35) KDM4EMAPTHKDC1TP53CYP3A4
SCHEMBL5181814 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116676293-A Polypeptides having cellobiohydrolase activity and polynucleotides encoding same 国投生物科技投资有限公司 2023-09-01 CN disclosed
CN-107532154-B Polypeptides having cellobiohydrolase activity and polynucleotides encoding same 国投生物科技投资有限公司 2022-09-27 CN disclosed
CN-108350044-B Polypeptides having cellobiohydrolase activity and polynucleotides encoding same 诺维信公司 2022-05-24 CN disclosed
CN-113302305-A Methods of increasing productivity of filamentous fungal cells in the production of polypeptides 诺维信公司 2021-08-24 CN disclosed
CN-113302293-A Polypeptides having xylanase activity and polynucleotides encoding same 诺维信公司 2021-08-24 CN disclosed