2,6-Dimethoxyquinone

2,6-Dimethoxyquinone

SCHEMBL570683

COC1=CC(=O)C=C(OC)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 2/20 1.00
KDM4E B2RXH2 1/20 1.00
MEN1 O00255 1/20 1.00
USP2 O75604 1/20 1.00
TP53 P04637 1/20 1.00
CYP3A4 P08684 1/20 1.00
MAPT P10636 1/20 1.00
MAPK1 P28482 1/20 1.00
KMT2A Q03164 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
ALOX5 P09917 7/20 0.70
PTGS2 P35354 6/20 0.70
ERBB2 P04626 1/20 0.56
TYR P14679 1/20 0.56
GLS2 Q9UI32 3/20 0.52
TEK Q02763 2/20 0.52
CDC25A P30304 2/20 0.48
CDC25B P30305 2/20 0.48
CDC25C P30307 1/20 0.48
IDO1 P14902 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Dimethoxyquinone SCHEMBL1706801 0.86 KDM4E (0.74) HKDC1KDM4EMEN1USP2TP53
SCHEMBL684719 0.85 MAPT (0.73) HKDC1KDM4EMEN1USP2TP53
2,6-Dimethoxyquinone SCHEMBL11304693 0.84 HKDC1 (0.71) HKDC1KDM4EMEN1USP2TP53
SCHEMBL21729822 0.83 HKDC1 (0.70) HKDC1KDM4EMEN1USP2TP53
SCHEMBL9364524 0.83 MAPT (0.70) HKDC1KDM4EMEN1USP2TP53
SCHEMBL7115894 0.83 ALOX5 (1.00) HKDC1KDM4EMEN1USP2TP53
SCHEMBL197028 0.82 HKDC1 (0.70) HKDC1KDM4EMEN1USP2TP53
Ubiquinone Qo SCHEMBL6760403 0.78 HKDC1 (0.63) HKDC1KDM4EMEN1USP2TP53
SCHEMBL10824988 0.78 HKDC1 (0.64) HKDC1KDM4EMEN1USP2TP53
SCHEMBL2404062 0.78 HKDC1 (0.61) HKDC1KDM4EMEN1USP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217103-A1 DURABLE ION EXCHANGE MEMBRANES WITH ADDITIVES W. L. GORE & ASSOCIATES, INC. (US) 2025-10-16 WO claimed
US-20250262169-A1 METHODS OF TREATING COENZYME Q10 DEFICIENCY THLIVERIS, ANDREW T. 2025-08-21 US claimed
CN-119419302-A Lithium-fluorocarbon battery electrolyte containing redox medium and preparation method and application thereof 中国科学院长春应用化学研究所 2025-02-11 CN claimed
CN-119139480-A Composition for increasing solubility of quinone compounds and application thereof 沈阳药科大学 2024-12-17 CN claimed
WO-2024166382-A1 PRIMARY BATTERY 日本電信電話株式会社 2024-08-15 WO claimed
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP claimed
CN-113698039-B Urine harmless treatment method and system and intelligent toilet based on urine harmless treatment method and system 中云汇(成都)物联科技有限公司 2024-03-22 CN claimed
CN-113950520-B Liquid composition for selective removal of polysilicon relative to p-doped silicon and silicon-germanium during semiconductor device fabrication 弗萨姆材料美国有限责任公司 2024-03-01 CN claimed
CN-117491534-A Method for detecting content of benzoquinone compound in wood 广电计量检测(重庆)有限公司 2024-02-02 CN claimed
CN-117256396-A Complex operation method of endangered plant garlic fruits and medicinal plants 广西壮族自治区林业科学研究院 2023-12-22 CN claimed
US-20020098979-A1 Method of controlling zoological and aquatic plant growth CUTLER STEPHEN J (US) 2002-07-25 US claimed
WO-2001060971-A2 METHOD OF CONTROLLING ZOOLOGICAL AND AQUATIC PLANT GROWTH GARNETT, INC. (US) 2001-08-23 WO claimed
EP-0005140-B1 NOVEL 4-DESOXY-THIAZOLO (5,4-C) RIFAMYCIN DERIVATIVES AND A PROCESS FOR PREPARING THEM GRUPPO LEPETIT S.P.A. (IT) 1982-10-27 EP claimed
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US claimed
US-4234485-A REACTING RIFAMYCIN S, CYSTEINE OR CYSTEAMINE, AN OXIDIZER, AND A HYROXYAMINE, A HYDRAZINE, OR A HYDRAZIDE; ONE-STEP GRUPPO LEPETIT S.P.A. (IT) 1980-11-18 US claimed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
EP-0005140-A2 Novel 4-desoxy-thiazolo (5,4-c) rifamycin derivatives and a process for preparing them GRUPPO LEPETIT S.P.A. (IT) 1979-11-14 EP claimed
US-4144234-A Preparation of rifamycin P and Q derivatives GRUPPO LEPETIT S.P.A. (IT) 1979-03-13 US claimed
US-4129562-A ANTIBACTERIAL AGENTS WITH LOW TOXICITY GRUPPO LEPETIT S.P.A. (IT) 1978-12-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250262169-A1 METHODS OF TREATING COENZYME Q10 DEFICIENCY NDUFB10, NDUFA10, NDUFB11 HKDC1 1832/4885KDM4E 3592/4885MEN1 1538/4885
US-20020098979-A1 Method of controlling zoological and aquatic plant growth ANTXR2, NQO2, CYP4A22 HKDC1 2141/4885KDM4E 2692/4885MEN1 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.